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The effect of fluvoxamine on the pharmacokinetics of a single four mg dose tizanidine of Zanaflex was studied in 10 wholesome subjects. The Cmax, AUC, and half-life of tizanidine elevated by 12- fold, 33-fold, and 3-fold, respectively. The impact of ciprofloxacin on the pharmacokinetics of a single 4 mg dose of Zanaflex was studied in 10 healthy subjects. Buy cheap tizanidine 10mg in china. Other Uses For This Medicine Muscle relaxant reflexology to treat. Muscle relaxants are medicines that are used to prevent or reduce muscle spasms and spasticity. Spasticity happens when muscle tissue contract tightly and become stiff and tougher to make use of. Animal studies have decided that this drug causes fetal hurt Label. Similar to clonidine, tizanidine causes dose-related sedation, more so compared with methocarbamol and baclofen.Predominantly used in patients with spasticity related to a number of sclerosis and spinal cord damage, tizanidine has found its functions in continual musculoskeletal ache conditions related to muscle tightness.The median dose during the plateau phase ranged from 20–28 mg/day.The usual dosage is 2 to four mg orally, normally at evening to facilitate sleep. Spasticity These medications can decelerate the breakdown of tizanidine and lead to elevated sedation, drowsiness and slowed reflexes. You could take tizanidine with or without food, but take it tizanidine the identical method each time. Switching between taking tizanidine with food and taking it with out food can make the drugs much less efficient or cause elevated unwanted effects.
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