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In fact, 60% to 80% of dopaminergic neurons are usually lost by the time a patient is diagnosed with Parkinson's disease.

Patients may have reported multiple adverse experiences during the study or at discontinuation; thus, patients may be included in more than one category.

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It is also used to treat Restless Legs Syndrome.

Zinbryta (daclizumab) is an interleukin-2 receptor blocking antibody indicated for the treatment of relapsing.

PD, Neupro has been compared with placebo (a dummy treatment).

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Letter to the Editor: Update to the AASM clinical practice guideline: The treatment of restless legs syndrome and periodic limb movement disorder in addults--an update for 2012: practice paramters with an evidence-based systematic review and meta-anayysis.

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All groups in the study showed improvements from baseline in each of these measures at the 12-week evaluation, including those assigned to placebo.

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The syndrome is thought to be caused by problems in the way dopamine works in the brain, which may be corrected by pramipexole.

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Pramipexole is associated with 3 rare but serious side effects: sleep attacks, which have only occurred in Parkinson's disease; compulsive behaviors and pathologic gambling, which have occurred in Parkinson's disease and restless legs syndrome; and psychosis, which has occurred in both psychiatric and neurologic populations.

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