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Weight Gain From Steroids Steroids (such as prednisone or dexamethasone) may cause your child to gain excess weight. Steroids can cause an increase in appetite and a build up (retention) of fluid. Will usually lose weight after the steroids are stopped.
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It has long been known that the administration of antihistamines can cause weight gain. In fact, one antihistamine, cyproheptadine, has been used for this purpose. One reason, which may be the most reasonable, is that histamine is known to reduce the appetite, and antihistamines, therefore, counteract this effect.
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