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It is not affected by cooking, and in Japan dozens of people are poisoned every year by eating pufferfish fugu prepared by chefs who have not been trained to remove the poisonous parts.

The optimal tiotropium treatment regimen for patients with asthma was examined in two phase II studies.

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Second, in our study, a higher proportion of patients with sustained abstinence from smoking tobacco may have resulted in a lower mean rate of decline.

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Evidence was obtained through a systematic review of peer-reviewed literature (up to November 2010) using the databases MEDLINE, PubMed, EBSCO, Ovid, and the Cochrane Collaboration's Database for Systematic Reviews.

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One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium.

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The most obvious question is, does obestatin work in obese animals.

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If you recommend titration of O 2, what saturation would you consider too high and what saturation would you consider hypoxemia?

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Avoid getting the powder from a tiotropium capsule in your eyes.

At that time, results of the UPLIFT trial were not published yet.

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Tiotropium inhalation may also be used for purposes not listed in this medication guide.

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Los investigadores examinaron la informacin sobre los historiales laborales de los participantes hasta los 42 aos de edad.

To put it differently generics have identical active ingredients and their pharmacological effects are the same, as those of their brand-name equivalents.

Please consider the pros and cons of any medication.

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SPIRIVA is only used to prevent bronchospasm attacks.

Drugs metabolized via the CYP450 system, such as theophylline and warfarin, may be affected.

Your doctor may prescribe a number of different medications.

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This therapy is also recommended for use in asthma but only for management of exacerbations to maintain SaO 2 at 90% or greater.

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Adverse events were reported by 90% of the patients in the study, and serious adverse events were reported by 41% of the patients ( Table 4 Adverse Events among 6184 Patients in the Safety Population and 658 Patients in the Substudy of Bone Mineral Density.

COPD is characterized by a progressively increasing airflow obstruction that cannot be fully reversed, although it can sometimes be temporarily improved by medications.

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Clinicians should base the choice of specific monotherapy on patient preference, cost, and adverse effect profile.

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The time to the first exacerbation (the primary end point) was increased by 42 days with tiotropium as compared with salmeterol (187 days vs.

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The CDC said that patientrelated factors that impact adherence typically worsen with more complex drugs.

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We have entered an era of increasingly frequent publication of meta-analyses, some of which identify potential safety signals.

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There are insufficient data to recommend short courses of high-dose ICS in children with mild, intermittent asthma exacerbation.

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Consultation with a specialist is recommended for patients who require this step of therapy (Evidence D).

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Many pulmonary diseases impact and have interactions with sleep.

Antimicrobial resistance is a major clinical and public health issue and a threat to the future of healthcare.

Gingival hyperplasia, overgrowth of the gum tissue, is common in patients taking anticonvulsants, immunosuppressant drugs, and calcium channel blockers taken by cardiac patients.

Consultation with a specialist is recommended for patients whenever there is a difficulty in achieving control (Evidence D).

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Specifically, it is considered as an anticholinergic or antimuscarinic because it binds with muscarinic receptors in the airway to relax smooth muscles.

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Your age, height and sex affect your lung volumes.

Some people need to use an inhaler regularly.

For others, though, a thunderstorm may be a brutal trigger for a headache.

Relief medication use was also recorded daily via electronic diaries.

The higher the dose of anticholinergic drugs and the longer such medications were taken, the greater the risk of dementia.

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Over time, disease progression often differs between asthma and COPD.

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Use of stem cell therapy to repair the slow, steady damage done to heart muscle and improve heart function is safe, but has not been shown to improve most measures of heart function, the study authors said.

Head of Department of Pulmonary Diseases and Tuberculosis, University Medical Center Groningen, Post Box 30.

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Aguilaniu B: Impact of bronchodilator therapy on exercise tolerance in COPD.

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This causes a reduction in dynamic hyperinflation at rest and during exercise with consequent improvement in exercise tolerance ().

PANDAS, rheumatic fever, and Sydenham chorea.

Consider the second situation in which the same patient is prescribed marketed tiotropium upon discontinuation of study drug and dies 3 years later.

Since dizziness and blurred vision may occur with the use of Spiriva HANDIHALER, caution patients about engaging in activities such as driving a vehicle or operating appliances or machinery.

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The estimated incidence is 1 million cases per year, with most effusions caused by congestive heart failure, malignancy, infections, and pulmonary emboli.

More than 15 years ago, I was an investigator of the in which 5000 smokers with mild to moderate COPD were randomized to take Atrovent (ipratropium) or a placebo for five years.

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Whenever there is a difficulty to control asthma at step 4, it is strongly recommended to refer patient to a physician specialized in asthma.

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All of the studies reported the number of participants with one or more exacerbation in each treatment group.

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It is therefore important to take into account the uncertainty around these estimations.

Today, older healthcare consumers or their representatives are often informed and savvy and may request every treatment available.

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Adenosine receptor antagonism also contributes to the brochodilatory effect of theophylline ().

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For example, the guideline does not apply to women who go through menopause early or prematurely, at age 45 or younger, Faubion said.

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